Pancreatic cancer is one of the deadliest cancers. Fewer than 13 percent of those diagnosed survive more than five years. But after receiving a new mRNA vaccine, nearly 90 percent are still alive six years later.
The share of older people with dementia at any given age has fallen by two-thirds over 40 years. An 85-year-old in 2024 has one-third the risk of having dementia compared to an 85-year-old in 1984.
Hookworm infects more than 100 million people and is a major cause of iron-deficiency anemia, particularly in children and pregnant women. A phase 2 trial shows that a vaccine candidate substantially reduces the intensity of infection.
The number of overdose deaths in the US is estimated to have fallen by 35 percent from the peak year of 2023 to 2025. The purity of seized fentanyl powder was cut in half between August 2023 and the end of 2024. A coordinated counter-narcotics strategy has choked off the supply of fentanyl.
Globally, maternal mortality has decreased by 40 percent since 2000, according to estimates from the UN Maternal Mortality Estimation Inter-Agency Group. A sepsis prevention program at 59 hospitals in Malawi and Uganda reduced infection-related maternal mortality by 32 percent.
Startups that learned how other companies had reorganized their operations around AI found 44 percent more use cases for the technology. The startups that received this information had 1.9 times higher revenue and were 18 percent more likely to acquire paying customers.
There has long been strong evidence that general intelligence is heritable. Now a large meta-analysis shows the same applies to abilities like math and language. The findings open up the possibility of using genetic profiles to tailor education to each child's cognitive strengths and weaknesses.
Emissions have already fallen by 34 million tonnes of CO2 โ equivalent to permanently shutting down eight coal-fired power plants. The steel industry accounts for 7 percent of global emissions, and China produces more than half of the world's steel.
An AI system has for the first time solved a problem from FrontierMath, a benchmark consisting of real research problems that mathematicians have failed to solve. Multiple AI models have now demonstrated the ability to solve the problem, including GPT-5.4 Pro, Gemini 3.1 Pro, and Claude Opus 4.6.