A five-in-one vaccine has begun to be used in several African countries to protect against bacterial meningitis. The vaccine costs only three dollars per dose and protects against four types of bacteria that cause almost all meningitis epidemics in the region.
Over 1.2 billion unique children have been vaccinated against a range of deadly diseases through routine vaccination since 2000.
Deaths from diarrhea among children under five have dropped from 3.1 million annually in 1997 to 340,000 today. Rotavirus vaccines that cost $200 per dose in the 2000s now cost about one dollar. Since 1990, 2.6 billion people have gained access to safe drinking water.
Child mortality in Bangladesh has dropped from 211 per 1,000 births in 1979 to 31 per 1,000 today. Vaccination coverage has increased from 2 percent to 98 percent for basic vaccines. The country now finances 39 percent of its vaccination program and will become completely self-sufficient by 2030.
The clinical trial of potentially first new tuberculosis vaccine in a century has successfully recruited all 20,000 participants several months earlier than planned. The vaccine showed 50% effectiveness in earlier phase 2 studies, which could reduce millions of tuberculosis cases globally.
A clinical trial showed that the drug lenacapavir protected 100 percent of women and girls against HIV infection. The drug only needs to be injected twice a year to provide full protection. New results suggest that an annual injection may be sufficient for long-lasting protection.
The Ervebo vaccine has demonstrated over 95 percent effectiveness against the Zaire strain of the Ebola virus. The vaccine is now used as a cornerstone in the fight against Ebola and has been successfully deployed in several African countries as a preventive measure.
Patients who developed an immune response from the personalized cancer vaccine have not yet experienced recurrence after more than three years of follow-up. The vaccine creates T cells that can live for up to 100 years and retain their ability to identify and fight cancer cells.
Patients who received a personalized cancer vaccine and developed an immune response lived longer without relapse. The T-cells created by the vaccine remained in the body for about 3 years and continued to fight cancer cells.