A clinical trial showed that the drug lenacapavir protected 100 percent of women and girls against HIV infection. The drug only needs to be injected twice a year to provide full protection. New results suggest that an annual injection may be sufficient for long-lasting protection.
The Ervebo vaccine has demonstrated over 95 percent effectiveness against the Zaire strain of the Ebola virus. The vaccine is now used as a cornerstone in the fight against Ebola and has been successfully deployed in several African countries as a preventive measure.
Patients who developed an immune response from the personalized cancer vaccine have not yet experienced recurrence after more than three years of follow-up. The vaccine creates T cells that can live for up to 100 years and retain their ability to identify and fight cancer cells.
Patients who received a personalized cancer vaccine and developed an immune response lived longer without relapse. The T-cells created by the vaccine remained in the body for about 3 years and continued to fight cancer cells.
The number of malaria deaths in Kenya has decreased by 93 percent. Approximately 400,000 children in western Kenya have received the RTS,S malaria vaccine, the world's first of its kind. The country has distributed 15.3 million insecticide-treated mosquito nets.
Measles vaccines have saved 94 million lives globally since 1974, of which 92 million were children. The measles vaccine has saved more lives than any other childhood vaccine in the last 50 years.
Unlike most other cancers, cervical cancer can be prevented and completely eliminated using existing tools. Several high-income countries are close to elimination, with fewer than four cases per 100,000 women.
Scientists have developed a new method to vaccinate against malaria by letting genetically modified malaria parasites transfer via mosquito bites. The method provided 89 percent protection against malaria in the initial study.
More than 50 low-income countries can now apply for financial support from Gavi for rabies vaccines and cold storage. North and South America have reduced rabies cases by over 95 percent through dog vaccination.